Ionis Pharmaceuticals Inc (IONS)

Biotechnology

IONS · NASDAQ NMS - GLOBAL MARKET · USD

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$83.18

+1.69%

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Price · 1 year

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Intrinsic Investor is for education and research only — not financial advice.

Key metrics

EPS

$-2.38

ROE

-67.6%

Gross margin

10.9%

Debt/Equity

5.31x

Revenue growth

87.0%

Ionis Pharmaceuticals Inc — company intelligence

Earnings surprises

Q1 2026$-0.56 vs $-0.93 est+39.7%

Q4 2025$-1.41 vs $-1.35 est-4.6%

Q3 2025$-0.80 vs $-1.26 est+36.4%

Q2 2025$0.70 vs $-0.44 est+259.6%

Analyst consensus · 33 analysts

27 Buy6 Hold0 Sell

Updated Jul 6, 2026

Insider activity · 90 days

16 buys15 sellsnet -113,290 shares

Hayden Michael RBuy 2,301 · Jul 1, 2026

BERTHELSEN SPENCER RBuy 2,301 · Jul 1, 2026

BERTHELSEN SPENCER RBuy 5,369 · Jul 1, 2026

Recent SEC filings

8-K — Material event reportJul 10, 2026

4 — Insider transaction reportJul 9, 2026

Latest news

Ionis Pharmaceuticals Completes Enrollment In Pivotal Cohort (Cohort 1) Of REVEAL Phase 3 Reveal Study Of Obudanersen (ION582) Angelman Syndrome; Adult Cohort (Cohort 2) Is Expected To Complete Enrollment In Q3 2026; Topline Data Expected In 2H 2027 — Benzinga · 5d ago

Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval of TRYNGOLZA for Severe Hypertriglyceridemia and Acute Pancreatitis Risk Reduction - Slideshow — SeekingAlpha · 2w ago

Ionis Pharmaceuticals, Inc. (IONS) Discusses FDA Approval of TRYNGOLZA for Severe Hypertriglyceridemia and Acute Pancreatitis Risk Reduction Transcript — SeekingAlpha · 2w ago

Goldman Sachs Maintains Neutral on Ionis Pharmaceuticals, Raises Price Target to $75 — Benzinga · 2w ago

Ionis Climbs As FDA Clears New Therapy To Lower Triglycerides, Pancreatitis Risk — Benzinga · 2w ago

AI Valuation Narrative

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